Page last updated: April 2025
The information on this webpage was adapted from Understanding Bowel Cancer - A guide for people with cancer, their families and friends (2025 edition). This webpage was last updated in April 2025.
Expert content reviewers:
This information was developed based on Australian and international clinical practice guidelines, and with the help of a range of health professionals and people affected by bowel cancer:
- Prof Alexander Heriot, Colorectal Surgeon and Director Cancer Surgery, Peter MacCallum Cancer Centre, Director, Lower GI Tumour Stream, Victorian Comprehensive Cancer Centre, VIC
- Dr Cameron Bell, Gastroenterologist, Royal North Shore Hospital, NSW
- Graham Borgas, Consumer
- Prof Michael Bourke, Director of Gastrointestinal Endoscopy, Westmead Hospital, The University of Sydney, NSW
- Laura Carman, 13 11 20 Consultant, Cancer Council Victoria, VIC
- Amanda Connolly, Specialist Bowel Care Nurse, Icon Cancer Centre Windsor Gardens, SA
- A/Prof Melissa Eastgate, Operations Director, Cancer Care Services, Royal Brisbane and Women’s Hospital, QLD
- Anne Marie Lyons, Stomal Therapy Nurse, Concord Repatriation General Hospital and NSW Stoma Ltd, NSW
- Lisa Nicholson, Manager Bowel Care Services, Bowel Cancer Australia, NSW
- Stefanie Simnadis, Clinical Dietitian, St John of God Subiaco Hospital, WA
- Rafi Sharif, Consumer
- Dr Kirsten van Gysen, Radiation Oncologist, The Nepean Cancer and Wellness Centre, NSW
- Sarah Williams, Clinical Nurse Consultant, Lower GI, Peter MacCallum Cancer Centre, VIC
Some people have tests for bowel cancer because they have symptoms; others have no symptoms but have tests because of a strong family history of bowel cancer or after receiving a positive result through the National Bowel Cancer Screening Program.
If your doctor suspects you have bowel cancer, you may have some of the tests described in this chapter, but you are unlikely to need them all. Some tests may be repeated during or after treatment to check how well treatment is working.
It may take up to a week to get your test results. If waiting for test results makes you feel anxious, it may help to talk to a friend or family member, or call Cancer Council 13 11 20 for support.
Your guide to best cancer care
A lot can happen in a hurry when you’re diagnosed with cancer.
The guide to best cancer care for bowel cancer can help you make sense of what should happen. It will help you with what questions to ask your health professionals to make sure you receive the best care at every step.
Read the guide
General tests
Physical examination
Your doctor will ask to feel your abdomen for any swelling. To check for problems in the rectum and anus, they may also do an internal examination. The doctor puts a gloved, lubricated finger into the anus to feel for any lumps or swelling.
This is called a digital rectal examination (DRE). If you feel embarrassed or scared about a DRE, let your doctor know. A nurse may be present, but you can also ask for a family member or friend to be in the room with you for support.
The DRE may be uncomfortable, but it shouldn’t be painful. Because the anus is a muscle, it can help to try to relax during the examination.
The pressure on the rectum might make you feel like you are going to have a bowel movement, but it is very unlikely that this will happen.
Blood test
You may have a blood test to check your general health and look for signs that you are losing blood from your bowel.
The blood test may measure chemicals from your liver and check your red blood cell count (haemoglobin level). Having low red blood cells (anaemia) is common with bowel cancer, but it may also be caused by other conditions.
Checking your faeces (poo) for signs of blood
A test called the immunochemical faecal occult blood test (iFOBT) looks for tiny amounts of blood in your faeces. It is commonly used as a screening test for bowel cancer.
An iFOBT is generally not recommended for people who are bleeding from the rectum or have other bowel symptoms (e.g. a change in bowel habit, anaemia, unexplained weight loss, abdominal pain).
People with these symptoms are usually referred for a colonoscopy straightaway.
For an iFOBT, you usually collect a sample of your faeces at home. The sample is sent to a laboratory and examined for traces of blood, which may be a sign of polyps, cancer or another condition.
Only a small number (around 3–4%) of positive iFOBT tests are due to cancer or large precancerous polyps; more commonly the traces of blood are from benign conditions like haemorrhoids.
However, if the test finds blood in your faeces, your doctor will recommend you have a colonoscopy.
Screening test for bowel cancer
Screening is the process of looking for cancer or abnormalities that could lead to cancer in people who do not have any symptoms.
It is particularly important for bowel cancer, which often has no symptoms in its early stages.
Screening program
Through the National Bowel Cancer Screening Program, people aged 50–74 are automatically sent a free iFOBT kit every 2 years, and people aged 45–49 can request a free test to be sent to them.
You do the test at home and send it back. You don’t need to change what you eat or stop taking your medicines. A test kit can also be purchased from some pharmacies or online.
If the screening test is negative, it means no traces of blood were found in your sample and you’ll be sent another test in two years. If you have symptoms between screening tests, let your doctor know.
If the screening test is positive, it means there were traces of blood in your sample and you need more tests. It is important to do the screening test, as it can find early cancers and some precancerous polyps in the bowel.
Removing polyps reduces the risk of developing bowel cancer. Finding bowel cancer early improves the chance of surviving the disease.
If you want to order a test, have questions about how to do the test, need to update your contact details, or haven’t received your test kit, visit the National Bowel Cancer Screening Program.
You can also learn more about bowel screening for First Nations communities.
People with a higher risk
The National Bowel Cancer Screening Program is for people without symptoms of bowel cancer. If you have:
- symptoms of bowel cancer – talk to your doctor about having a colonoscopy or other tests
- another bowel condition, such as chronic inflammatory bowel disease – talk to your doctor about how they will monitor your risk of developing bowel cancer
- a strong family history or a genetic condition linked to bowel cancer – talk to your doctor about when you need to start iFOBTs or screening colonoscopies.
Tests to find cancer in the bowel
Colonoscopy, polypectomy and biopsy
Colonoscopy
This is the main test to look for bowel cancer. It lets your doctor look at the lining of the entire large bowel. Before a colonoscopy, you clear out the bowel with a preparation.
It’s very important to follow the instructions – the cleaner the bowel, the more likely it is that the doctor can see polyps or areas of concern.
Most colonoscopies are done as day surgery at a hospital. On the day of the procedure, you will usually be given a sedative or light anaesthetic so you don’t feel anything. This will make you drowsy or may put you to sleep.
A colonoscopy usually takes 20–30 minutes. During the procedure, the doctor puts a colonoscope (a flexible tube with a camera on the end) through your anus and up into the rectum and colon.
Carbon dioxide or air is passed through the colonoscope to inflate the colon and make it easier for the doctor to see the bowel.
Polypectomy
During the colonoscopy, any precancerous polyps will be removed – this is called a polypectomy. Most polyps are small (less than 1 cm) and the procedure is very safe and usually has no side effects.
Biopsy
If the doctor sees abnormal-looking areas, including polyps, they will remove a sample of the tissue. This is called a biopsy. A pathologist looks at the sample under a microscope to check for cancer or specific gene changes.
Side effects
You may be weak or drowsy so someone will need to take you home afterwards. You won’t be able to drive until the day after your procedure. The gas used to inflate the bowel can sometimes cause bloating or wind pain.
Rare complications include bleeding, or damage to the bowel (perforation) or spleen. Your doctor will explain the risks.
Less commonly used tests
CT colonography
Also called a virtual colonoscopy, it uses a CT scanner to create images of the colon and rectum. Bowel preparation is usually needed before the test. A CT colonography is done by a radiologist (who analyses x-rays and scans).
You may have a CT colonography if a colonoscopy didn’t show all of the colon or when a colonoscopy is not safe. However, a CT colonography is not often used because it exposes you to radiation and is not as accurate as a colonoscopy.
It can see only bigger polyps, not small ones. If any abnormality is detected, you will need to have a colonoscopy so that the doctor can take tissue samples. A CT colonography is covered by Medicare only in limited circumstances.
Flexible sigmoidoscopy
This test is similar to a colonoscopy but only lets the doctor see the rectum and about the lower half of the colon (sigmoid and descending colon). Before a flexible sigmoidoscopy, you will need to have a light bowel clean-out, usually with an enema.
You may be given light sedation for the procedure. You will then lie on your left side while a colonoscope (or, sometimes, a shorter but similar tube called a sigmoidoscope) is put into your anus and guided up through the bowel.
The colonoscope or sigmoidoscope blows carbon dioxide or air into the bowel to inflate it slightly so the doctor can see the bowel wall more clearly.
A light and camera at the end of the colonoscope or sigmoidoscope show up any unusual areas or polyps, and your doctor can take tissue samples (biopsies).
Bowel preparation
Before some tests, you will have to empty your bowel completely so the doctor can see the bowel clearly. This is called bowel preparation (or washout) and can vary, so ask your doctor what you need to do.
It’s important to follow the instructions so you don’t have to repeat the test.
- Change diet – For 5–7 days before, don’t eat any seeds or grains – including fruit and vegetables that contain seeds (e.g. tomatoes and kiwifruit). For breakfast, morning tea and lunch the day before, eat from the white food diet, which includes white rice, white bread, white potato, cheese, eggs, white fish, skinless chicken breast, plain pasta or rice noodles, milk, plain yoghurt and mayonnaise.
- Drink clear fluids – After lunchtime the day before your test, you will usually have nothing but clear fluids (e.g. clear apple juice, certain coloured sports drinks and soft drink, broth, water, black tea and coffee). The fluids will help to prevent dehydration.
- Take prescribed laxatives – You will be prescribed a strong laxative as a powder to mix with water, or as a tablet. You will take the laxative over several hours, starting 12–18 hours before the test. This will cause you to have several episodes of watery diarrhoea and you will need to stay home to be near a toilet.
- Have an enema, if required – One common way to clear the lower part of the bowel is using an enema. You may be given an enema by a nurse at the hospital before a colonoscopy if the laxative hasn’t completely cleaned out the bowel, or if you are only having a flexible sigmoidoscopy. An enema involves putting liquid directly into the rectum. The liquid washes out the lower part of the bowel, along with any faeces.
Further tests
If tests show you have bowel cancer, more tests will be done to see if it has spread to other parts of your body. Before you book any test, ask how much it will cost.
Before having scans, tell the doctor if you have any allergies or have had a reaction to dyes during previous scans.
You should also let them know if you have diabetes or kidney disease, are pregnant or breastfeeding, or are claustrophobic (afraid of confined spaces).
CEA blood test
You may be tested for carcinoembryonic antigen (CEA), a protein produced by some (not all) bowel cancers. Low levels are normal – but if you have a high level, your doctor may do more tests.
Smoking, pregnancy and other factors can also raise CEA levels. If CEA is high, it will be retested after treatment to see if it has returned to normal.
CT scan
A CT (computerised tomography) scan uses x-rays and a computer to create a detailed picture of the inside of the body. CT scans are usually done at a hospital or radiology clinic.
A dye is injected into a vein to make the pictures clearer. It may make you feel hot, have a strange taste in your mouth or feel that you need to urinate (wee or pee), but these sensations won’t last long.
During the scan, you lie still on a table that moves in and out of the machine. Your chest, abdomen and the area between your hip bones (pelvis) will be scanned to see if the cancer has spread to these areas.
The scan itself takes 5–10 minutes and is painless.
MRI scan
An MRI (magnetic resonance imaging) scan uses a powerful magnet and radio waves to create detailed pictures of the inside of your body. MRIs are mostly used only for cancers in the rectum, not cancers higher in the bowel.
An MRI may also be used to scan the liver if there was an abnormality seen on a CT scan that needs to be checked. Before the scan, let your medical team know if you have a pacemaker or any other metallic object in your body.
If you do, you may not be able to have an MRI scan as the magnet can interfere with some metallic objects. Newer devices are often safe to go into the scanner. Before the MRI, you may be injected with a dye to help make the pictures clearer.
During the scan, you lie on a table that slides into a large metal tube open at both ends. The noisy, narrow machine makes some people feel anxious or claustrophobic. If you might feel distressed, talk to your medical team beforehand.
You may be given medicine to help you relax. You will wear headphones or earplugs. The scan may take 30–90 minutes, depending on the area being scanned.
PET–CT scan
A positron emission tomography (PET) scan combined with a CT scan is a specialised imaging test. The two scans provide more detailed and accurate information about the cancer.
A PET–CT scan is most commonly used before surgery to help find out where the cancer has spread to in the body. It can also be used after surgery to check if the cancer has come back after treatment.
When you make the appointment for the scan, you will be given instructions to follow about how to prepare for the scan, including what you can eat and drink.
Before the scan, you will be injected with a glucose solution containing a small amount of radioactive material. Cancer cells show up brighter on the scan because they take up more glucose solution than the normal cells do.
You will then be asked to sit very quietly or lie down for 30–90 minutes as the glucose spreads through your body. Then you will have the scan itself, which usually takes around 30 minutes.
You will also usually have a CT scan, before or after the PET scan. Medicare will only cover the cost of a PET–CT scan for bowel cancer in limited circumstances. If this test is recommended, check with your doctor what you will have to pay.
Genomic testing
If you are diagnosed with bowel cancer, the tissue removed during surgery will usually have more tests.
Called genomic (or molecular) tests, they look for gene changes (mutations) and other features in the cancer cells that may cause them to multiply and grow.
Results can help decide which treatments may or may not work for you. Some targeted therapy drugs only work for people with a RAS gene mutation.
Immunotherapy drugs also only work for people with a fault in the gene that helps the cell’s DNA repair itself (called mismatch repair or MMR genes).
Learn more
Staging bowel cancer
The tests described in this chapter help show whether you have bowel cancer and whether it has spread from the original site to other parts of the body.
This is known as staging and it helps your health care team advise you on the best treatment options. The most common staging system for bowel cancer is the TNM system, which stands for tumour–node–metastasis.
The Australian Clinico-Pathological Staging (ACPS) system may also be used in some hospitals. The TNM system gives numbers to:
- how deep the tumour has gone into the bowel (T1–4)
- whether or not lymph nodes are affected (N1–2)
- whether the cancer has spread or metastasised outside the bowel (M0–M1).
Based on the TNM numbers, the doctor then works out the cancer’s overall stage. Around half of all bowel cancers in Australia are diagnosed at stage 1 or 2.
- Stage 1 – tumour is found only in the inner layers of the bowel wall.
- Stage 2 – tumour has spread deeper into the layers of the bowel wall.
- Stage 3 – tumour is in any layer of the bowel wall and has spread into nearby lymph nodes.
- Stage 4 – tumour has spread beyond the bowel to other parts of the body, such as the liver or lungs, or to distant lymph nodes.
The stage can be predicted before surgery based on the results of early tests, but may be revised after surgery, following tests on the cancer tissue and lymph nodes removed during surgery.
“I had very light blood streaks on toilet paper when wiping my bottom. After 2 weeks of this, I went to my doctor thinking it was haemorrhoids but he sent me for a colonoscopy.” Richard
Prognosis
Prognosis means the expected outcome of a disease. You may wish to discuss your prognosis and treatment options with your doctor, but it is not possible for anyone to predict the exact course of the disease.
Your doctor can give you an idea about the common issues that affect people with bowel cancer.
Generally, the earlier that bowel cancer is diagnosed, the better the chances of successful treatment, but people with more advanced bowel cancer may still respond well to treatment.
Test results, the type of cancer, the rate and depth of tumour growth, the likelihood of response to treatment, and factors such as your age, level of fitness and medical history are important in assessing your prognosis.